Weird rare diseases // Drug Repurposing

Weird rare diseases

Blue-skinned people? Vampire Syndrome? When we were kids, we couldn't hear enough about illnesses, horrid medical conditions or weird diseases. Not much has changed since then. When we hear about an outbreak of a flesh-eating bacteria or some other rare sickness, we're fascinated. But now we're also terrified. Some rare diseases are very real and if you catch them, you're a goner. Here's a list with 10 of the most rare diseases out there.

Elephantiasis: grossly enlarged members

Lymphatic filariasis, also known as elephantiasis, is best known from dramatic photos of people with grossly enlarged or swollen arms and legs. The disease is caused by parasitic worms, including Wuchereria bancrofti, Brugia malayi, and B. timori, all transmitted by mosquitoes. Lymphatic filariasis currently affects 120 million people worldwide, and 40 million of these people are seriously diseased. When an infected female mosquito bites a person, she may inject the worm larvae, called microfilariae, into the blood. The microfilariae reproduce and spread throughout the bloodstream, where they can live for many years. Often disease symptoms do not appear until years after infection. As the parasites accumulate in the blood vessels, they can restrict circulation and cause fluid to build up in surrounding tissues. The most common, visible signs of infection are excessively enlarged arms, legs, genitalia, and breasts.

Progeria: the 80-Year-Old Children

Progeria is caused by a single tiny defect in a child's genetic code, but it has devastating and life-changing consequences. On average, a child born with this disease will be dead by the age of 13. As they see their bodies fast forward through the normal process of ageing they develop striking physical symptoms, often including premature baldness, heart disease, thinning bones and arthritis. Progeria is extremely rare, there are only around 48 people living with it in the whole world. However, there is a family that has five children with the disease.

Werewolf Syndrome: the wolf people

When two year-old Abys DeJesus grew dark, hairy patches on her face, doctors said she has a condition known as Human Werewolf Syndrome. The disease is called werewolf syndrome because people with it look like werewolves - except without the sharp teeth and claws. In Mexico, a large family of men had hair that covered their faces and upper bodies. Two brothers were even offered a part in the X-Files but they turned down the offer.

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No not me

by kjeltring

But it seems that so many people I know are having weird complications...2 with rare orphan diseases attacking their immune syst, one Type 1 Diabetic insulin dependant whose condition just seems to get more complicated as she gets older...I dunno
this friend was so depressed on the phone a few secs ago

Yes and no...

by masie

...pigeons can get into a house in any number of ways, and are actually difficult to get out. it does not have to mean the house has had years of neglect.
...but you should be a little cautious. picgeons (and their droppings) can carry some rather weird diseases like psittacosis. this is rare, but can happen, and can have some nasty effects in humans.

People die from obesity

by ------

And diabetes and heart disease. Obesity is a risk factor for many diseases. Sure both are a problem but it's worth asking why there is so much attention focused on one disorder and not the other when one is a rare psychological disorder and the other is an epidemic. People who live in inner cities are likely to have few major supermarket chains or places to buy fruits and vegetables. Only recently has public pressure forced restaurants like McDonald's to offer a few healthy foods. There is an industry devoted to selling food with no nutritional value and a diet industry that encourages people to yo yo diet

Dowden Pub. Physicians Guide to Rare Diseases
Book (Dowden Pub.)

Five Best Friday Columns  — The Wire
People are also dying from hunger and once rare infectious diseases. Syria today is increasingly a failed state.

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