Rare skin shedding disease // Drug Repurposing

Rare skin shedding disease

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Former NBA star Manute Bol, the 7-foot-7 Sudanese tribesman who died at 47 on June 19, succumbed to kidney failure and a baffling, deadly skin disease called Stevens-Johnson syndrome.

Bol, a tireless humanitarian on behalf of Sudan, died in a Charlottesville, Va. hospital while suffering from the disease, which causes one's skin to shed.

Stevens-Johnson syndrome is a rare, serious disorder in a victim's skin, and mucous membranes react severely to a medication or infection. Often, according to experts, the syndrome begins with flu-like symptoms, followed by a painful red or purplish rash that spreads and blisters, eventually causing the top layer of skin to die and shed.

Bol's cousin, George Bol said doctors told the family that a "broad range of complications" led to his Manute's death.

Bol was on a charity mission to his native Sudan when an unusual series of medical conditions spiraled into a Stevens-Johnson syndrome reaction. Blisters from the syndrome were so severe that he was unable to eat or drink for 11 days.
"When he boarded the U.N. plane he left one bag behind due to space and he was separated (from) his medication, " said Tom Prichard, executive director of the Sudan Sunrise foundation, a Kansas City-area foundation for which Bol worked as a spokesman and fund raiser.

Bol's infection worsened, Prichard said, and he was sent to a hospital in Nairobi where he received medication for his kidney infection which ultimately led to the onset of Stevens-Johnson syndrome.

Stevens-Johnson syndrome is an immune system reaction that results in blisters on the skin and on the eyes, lips, mouth, and any other mucus membrane in the body.

"I think getting dehydrated was what contributed to his kidney failure, " Prichard said.

Severe blisters from Stevens-Johnson Syndrome often send patients to the intensive care unit and specialty burn centers, said Dr. Joseph Jorizzo, a member of the American Academy of Dermatology.

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It is slightly different with cats

by molly2s_mom

Sometimes vets never find out what causes it in cats.
"It is seldom that veterinarians can tell you why your cat developed pancreatitis. On very rare occasion, diseases like toxoplasmosis or, perhaps, physical injuries are the cause. Cats appear more adapted than dogs or humans to a high fat diet - so feeding high fat foods probably was not the cause of your cat’s pancreatic problem. What we do know is that, in most cases, pancreatitis in cats appears to be part of a continuous chronic inflammatory process going on within several of your pet’s organs."

Ardea Wildlife Pets Framed Print of Chiricahua Leopard Frog / Ramsey Canyon Leopard Frog - swallowing its shed skin from Ardea Wildlife Pets
Home (Ardea Wildlife Pets)
  • FRAMED PRINT This 22 x18 (56x46 cm) Framed Print features an image of Chiricahua Leopard Frog / Ramsey Canyon Leopard Frog - swallowing its shed skin chosen by Ardea...
  • Black Satin with Off-White Digital Mat 22x18 inch (559x457 mm) wooden frame with digital mat and RA4 print. Finished back including brown backing paper, hanging...
  • Image Description Chiricahua Leopard Frog / Ramsey Canyon Leopard Frog - swallowing its shed skin CAN-4046 Chiricahua Leopard Frog / Ramsey Canyon Leopard Frog...
  • For any queries regarding this image please contact Ardea Wildlife Pets quoting Reference 8183506
  • Image supplied and selected by Ardea Wildlife Pets. (c) John Cancalosi / ardea

Five Best Friday Columns  — The Wire
People are also dying from hunger and once rare infectious diseases. Syria today is increasingly a failed state.