Rare flesh eating disease // Drug Repurposing

Rare flesh eating disease

Matt Nichols holds his two-week-old baby, Ruby Ann, in his Bangor home. Nichols' wife, Heather, 29, passed away on August 8, 2013, at Eastern Maine Medical Center from necrotizing fasciitis, a flesh eating bacteria, that she contracted from an episiotomy during childbirth.BANGOR, Maine — Matt Nichols cradled his newborn daughter, Ruby Ann, in his arms Wednesday morning, gazing into her sleeping face.

When Matt, 29, accompanied his pregnant wife to Eastern Maine Medical Center on Aug. 1, he said he never could have imagined he’d raise their first child on his own after a vicious infection claimed the life of his wife just days after giving birth.Two-week-old Ruby Ann Nichols grasps her father, Matt's, finger. Heather Nichols, healthy and also 29 years old, had carried little Ruby through a normal pregnancy. She’d researched the ins and outs of pregnancy and childbirth, preparing herself to become a mother.

After 20 hours of labor, Heather gave birth with Matt at her side. A framed photo in the couple’s Bangor apartment shows her beaming, holding Ruby in her arms.

But, as Matt explained, things soon took a turn for the worse after the young family returned home. Matt said Heather had undergone an episiotomy, a small surgical incision that enlarges the vaginal opening to assist with childbirth, and the swelling and pain, while expected, worsened overnight.

A photo of Matt and Heather Nichols sits near their daughter Ruby's crib.The next morning, she returned to the hospital expecting a prescription for some medication. But Heather never left.

As Matt, Heather and their loved ones would discover over the following days, Heather had contracted a rare and rapidly spreading bacterial infection called necrotizing fasciitis, he said. Commonly known as “flesh-eating bacteria, ” the infection ravages muscles, fat and skin tissue, typically entering the body through a break in the skin, such as a cut or scrape.

The disease can be caused by several types of bacteria, most commonly group A Streptococcus, otherwise tolerable germs commonly found in the throat and on the skin. Infections from group A strep are usually easily treated, but in some cases produce toxins that can destroy the tissue they infect.

Matt Nichols adjusts his two-week-old daughter, Ruby's, blanket as she sleeps.“This one just came completely out of left field, ” Matt said. “Everybody I knew had never even heard of it.”

While necrotizing fasciitis is rare, its precise prevalence is hard to pin down because the condition itself doesn’t have to be reported to public health officials.

It occurs in fewer than 1 in 100, 000 reported hospital infections, said Dr. James Raczek, chief medical officer at EMMC.

Raczek said he could not confirm whether the hospital recently had recorded a case of necrotizing fasciitis. Asked to comment on Heather’s case, he declined, citing patient confidentiality rules.

In an email Wednesday afternoon, EMMC spokeswoman Jill McDonald wrote: “I can confirm that Heather Nichols is deceased.”

Matt Nichols holds his two-week-old baby, Ruby Ann, in his Bangor home. Two-week-old Ruby Ann Nichols.

You might also like

What Is Flesh Eating Disease?
What Is Flesh Eating Disease?
Rare flesh-eating disease kills mother who thought she had
Rare flesh-eating disease kills mother who thought she had ...

Girl W/ Flesh-Eating Disease Faces Horror/Depres

by bobrogve

Aimee Copeland, the Georgia student who lost her leg to a rare flesh-eating infection after a zip line injury, is smiling and laughing, according to her family. But the 24-year-old can't remember the events that landed her in critical condition, and faces an extreme psychological adjustment when she does.
"She will learn about the loss of her beautiful leg. She will discover that her hands lack the dexterity and tactile response she has known all her life," Copeland's father, Andy Copeland, wrote in a blog dedicated to his daughter's recovery. "How would you respond in such a situation? I think that moment will be one of horror and depression for Aimee

From eMedicine

by fwiw

* In the US: Although many cestode infestations occur worldwide, only a few are common in the United States.
Diphyllobothriasis is an infection that occurs from eating raw or undercooked fish infected with Diphyllobothrium species. Diphyllobothrium organisms are present in lakes, rivers, and deltas of freshwaters. Eskimos in western Alaska and the West Coast of the United States are frequent hosts.
Echinococcus multilocularis causes alveolar echinococcosis, which occurs only in the northern hemisphere. In the United States, it occurs particularly in Alaska. Echinococcus granulosis causes hydatid disease, which occurs worldwide

Vintage History 1928 photo Woman scientist recovers from rare disease contracted in laborator e3
Home (Vintage History)
  • 1928 photo Woman scientist recovers from rare disease contracted in laboratory sic experiments graphic.
  • Photograph size is approximately 8 x 10
  • Rare Historic Photograph
  • Archival Quality Reproduction

AGTC and SAFC Create Strategic Partnership to Provide Gene Therapy ..  — GlobeNewswire
AGTC's lead product candidates, which are each in the preclinical stage, focus on X-linked retinoschisis, achromatopsia and X-linked retinitis pigmentosa, which are rare diseases of the eye, caused by mutations in single genes, that significantly ..

Frederick Barnes (No. 47)
TV Series Episode Video on Demand ()
Library Images Historic Print (M): Woman scientist recovers from rare disease contracted in labratory [sic] experiments
Home (Library Images)
  • Typical Image Size: 11x14 , Print Size: 16x20.
  • Decorate with history or give a tasteful gift.
Sublime Gifts 1pc Premium Quality Rare Fluorite (Piece #U) From Germany Smooth Polished Worry Stone
Jewelry (Sublime Gifts)
  • 1pc Premium Quality Fluorite from Germany Smooth Polished Worry Stone
  • Just In! This One of a Kind Premium A+ Quality Rare Fluorite Smooth Polished Worry Stone is available in limited quantities. The Crystals were hand picked by us...
  • Aprx Size: 1 - 1 1/2
  • You will receive this exact Worrystone
  • Fluorite Gemstone meaning: Formerly called fluorspar, fluorite has a wide range of colors including yellow, blue, pink purple and green. It is an interesting and...
Vintage History 1936 photo U.S. opens war on social diseases. Washington, D.C., Dec. 28. The b9
Home (Vintage History)
  • 1936 photo U.S. opens war on social diseases. Washington, D.C., Dec. 28. The first nation-wide effort to combat venereal diseases was launched in Washington today...
  • Photograph size is approximately 8 x 10
  • Rare Historic Photograph
  • Archival Quality Reproduction