Rare brain diseases fatal // Drug Repurposing

Rare brain diseases fatal

Some diseases are very deadly to the brain tissues. Photo Credit

Many different things can affect brain function, from infection, to trauma, to metabolic imbalances, but only a few of them are deadly. Most of these deadly diseases are equal opportunity, infecting just as many people from First World countries as they do from underdeveloped nations. Only a few diseases are specific to one region or location in the world, while the rest of them can strike anyone at anytime.

The "mad cow" disease is caused by prions. Photo Credit

Prions are a type of highly infectious protein also known as transmissible spongiform encephalopathies (TSE). These proteins can infect different species and are always fatal. The CDC states that this disease kills by causing abnormal folding of cells in the brain and a rapid loss of cells, along with a decline in nervous function. Infection is caused by eating an infected animal. In addition, the Merck Manual states that the protein disease can be inherited or occur spontaneously.

A List of Fatal Human Brain DiseasesCreutzfeldt-Jakob disease is the most common form in humans. This is also the same as "Mad Cow" disease, but it can infect sheep, deer and elk in the same way. Kuru is another name for this disease that affects humans, but this name is given only to cannibalistic populations that become infected from eating the brains of an infected deceased human.

The Naegleria fowleri species of amoeba or parasite is found in infected warm freshwater and soil. An amoeba is a single-celled organism and can live outside the body, so it does not need the human host to survive. Death from this infection is one of the most rapid of the brain diseases, causing failure to thrive within three to seven days, according to the CDC. The amoeba often enters the brain through the nose while swimming and starts to destroy brain tissue immediately. Even with treatment, most of those infected die. While it is rapidly fatal, it is very rare. In the United States the CDC states there have only been 33 reported cases from 1998 to 2007.

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