Drug resistant gonorrhea treatment // Drug Repurposing

Drug resistant gonorrhea treatment

Drug-resistant gonorrhea: URGENTNot so long ago, gonorrhea was a common and easily treatable sexually transmitted disease. It was simply a matter of picking up the right antibiotics. However, the occurrence of gonorrhea cases that do not – or hardly – respond to antibiotic treatment is increasing in frequency. Since the disease is in many cases asymptomatic most people still seem to think it is nothing more than inconvenient. However if left untreated (or not treated adequately) gonorrhea can lead to more serious problems including pelvic inflammatory disease, infertility and complications in pregnant woman and infants.

Many different antibiotic-resistant gonorrhea strains are seen around the world nowadays. Varying from year to year, population to population. Some scientists see a spark of hope in that, eliminating the use of gonorrhea antibiotics that are becoming ineffective on a local scale, strains that are resistant to those drugs will decrease in prevalence so that the drugs will become useful once again.

Drug-resistant gonorrhea: URGENT

It is estimated by the Center for Disease Control and Prevention that around 30% of the (at least) 800.000 U.S. cases of gonorrhea involves a multi drug resistant strain. This resulted in the URGENT threat ranking of Neisseria gonorrhea in 2013. N. gonorrhea is showing resistance to antibiotics usually used to treat it. These drugs include: oral and injectable cephalosporins, azithromycin and tetracycline

In the United States Gonorrhea is among the most commonly notified infections. The CDC recently even updated its treatment guidelines to slow the emergence of drug resistance. CDC now recommends an antibiotic cocktail instead. (ceftriaxone plus either azithromycin or doxycycline).

Antibiotic Resistance ThreatsCephalosporin-resistant N. gonorrhoeae is often also resistant to other classes of antibiotics. As a result, empiric treatment is likely to fail in these cases. If cephalosporin-resistant N. gonorrhoeae becomes more widespread, the public health impact will be large. Additional cases of pelvic inflammatory disease, infertility, epididymitis and HIV infections are expected. (note: HIV is transmitted more readily when a person is co-infected with gonorrhea.)The estimated direct increase in medical costs are $235 million in the US alone.

Gonorrhea is a global problem, and requires a global approach. Rapid detection and effective treatment of patients and their partners could slow the spread of resistance. Only use a treatment that is tested to be effective against the infectious stain. (testing before treatment!)

In a few years, gonorrhea treatment will cease to be a simple process completely. If antibiotics are continued to be given without prior testing the effectiveness of the chosen treatment kicking an infection may require course after course of antibiotics, basically using patients as testtubes. Your best option then – the same as it is now - avoid getting infected in the first place.

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7th wonder of the world, Miracle Water

by everywhere252

PATANCHERU, India – When researchers analyzed vials of treated wastewater taken from a plant where about 90 Indian drug factories dump their residues, they were shocked. Enough of a single, powerful antibiotic was being spewed into one stream each day to treat every person in a city of 90,000.
And it wasn't just ciprofloxacin being detected. The supposedly cleaned water was a floating medicine cabinet — a soup of 21 different active pharmaceutical ingredients, used in generics for treatment of hypertension, heart disease, chronic liver ailments, depression, gonorrhea, ulcers and other ailments

Miracle water is free

by everywhere252

Miracle Water, 7th wonder of the world < - > 01/25 16:12:46
PATANCHERU, India – When researchers analyzed vials of treated wastewater taken from a plant where about 90 Indian drug factories dump their residues, they were shocked. Enough of a single, powerful antibiotic was being spewed into one stream each day to treat every person in a city of 90,000.
And it wasn't just ciprofloxacin being detected. The supposedly cleaned water was a floating medicine cabinet — a soup of 21 different active pharmaceutical ingredients, used in generics for treatment of hypertension, heart disease, chronic liver ailments, depression, gonorrhea, ulcers and other ailments

I do

by what_I_wouldnt_do

I'm also a CA state certified HIV test counselor and I can tell you that I don't tell clients a %. That would be meaningless. However, I can tell you from a personal perspective that although I think my risk of HIV is low, I practice safer sex with my partners because my risk of HPV (no cure and big link to cervical cancer), herpes (no cure and a HUGE annoyance), the many strains of hepatitis (none of which have cures and some of which can kill), chlamydia (can cause PID if untreated and often has no warning symptoms), and gonorrhea (which USED to be easily disposed of with antibiotics, but there are now strains in the U

Saunders Antibiotic and Chemotherapy (Expert Consult Title: Online + Print)
eBooks (Saunders)

Linda Cannon: Book covers gripping disease studies  — Joplin Globe
Other chapters cover the discovery of hantavirus out west, an ice cream linked outbreak of salmonella, the Legionnaire's disease outbreak and a refugee story that shows just how easily a widespread outbreak of any number of drug-resistant diseases ..