Drug resistant diseases // Drug Repurposing

Drug resistant diseases

Colorized 2005 scanning electron micrograph
This colored 2005 scanning electron micrograph (SEM) shows numerous clumps of methicillin-resistant Staphylococcus aureus bacteria, commonly referred to by the acronym, MRSA, magnified 2390 times. Credit: Janice Haney Carr/CDC/ Jeff Hageman, M.H.S.

In the war between drugs and drug-resistant diseases, is the current strategy for medicating patients giving many drug-resistant diseases a big competitive advantage?, asks a research paper that will be published in the Proceedings of the National Academy of Sciences.A scientist is dissecting mosquitoes under a microscope. Credit: B. Chan/The Read Group/Penn State. The paper argues for new research efforts to discover effective ways for managing the evolution and slowing the spread of drug-resistant disease organisms. The ultimate goal of this new research effort is to develop a new science-based model for drug-resistance management that will inform treatment guidelines for a wide variety of diseases that affect people, including malaria and other diseases caused by parasites, MRSA and other diseases caused by bacterial infections, AIDS and other diseases caused by viruses, and cancer.

The research paper, led by Andrew Read, professor of biology and entomology and director of the Center for Infectious Disease Dynamics at Penn State University, reports his lab's recent work on the effect of various medication strategies in groups of malaria-infected mice. "Our results indicate that the current strategy of aggressive use of medications to eliminate all targeted disease pathogens paradoxically gives drug-resistant pathogens the greatest possible evolutionary advantage, " Read said. "This universally accepted strategy - which has been the orthodox approach for many decades - may actually promote the proliferation of drug-resistant forms of infectious diseases." The question, says Read, is whether there are ways of treating patients that are equally good at making the patient healthy but give resistant parasites less of an advantage. Read is not arguing for changes in policy or for changes in doctor or patient behavior, but rather for the need for an improved knowledge base.

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You like to stir the pot. Good for you.

by sparkalina

People who eat the kings share of meat in this world (Americans) are selfishly deluding themselves...environmentally speaking of course.
Your over consumption is screwing everthing up.
Notice I didn't say consumption only, I think people will eat meat because it taste good, fine so be it, but you are seriously deluding your self when you buy crap from factory farms.
Pollution is created, antibiotics are ingested, and drug resistant diseases are created (the new bird flu just waiting to erupt)...
good times eh.
If by not supporting factory farming is being sick, hand me the nearest straightjacket...

OP needs to stop whining

by --

No it's not enough.
1. You are a doctor, drug resistant diseases are part of your job
2. prison guard. You are sitting around watching something, might as well be a prisoner.
3. American criminals don't exist. No wait they do, put down the donut and do your job.
Freakin walking stereotypes. You're so high and mighty that you think someone must beg for you to do your job. Bullcrap. Now 10 bucks says some idiot will do a parody post after this. I hope he chuckles so hard his mom throws him out of the house at the age of 40 and tells him to get a job already.

Guess what dude,

by bittersuite

Social Secuirty goes away, your employer saves on the portion he pays (but you won't see it in your check), and your income taxes increase because we'll have a bunch of smelly homeless people, who like yourself, failed to save for a rainy day ... or who invested in something "hot" like a dot bomb or a substandard mortagage.
and since that's a SOCIAL problem (drug resistant diseases, crime rates, etc.), someone has to pay for it.
So, put the credit card down, stop giving your income away for toys, and open an IRA.

Book (PN)

Linda Cannon: Book covers gripping disease studies  — Joplin Globe
Other chapters cover the discovery of hantavirus out west, an ice cream linked outbreak of salmonella, the Legionnaire's disease outbreak and a refugee story that shows just how easily a widespread outbreak of any number of drug-resistant diseases ..