What is drug development?
We then let the Chair of the Initiative’s Steering Committee, Dr. Patrick Wen of Dana-Farber Cancer Institute, explain the promise of this effort further in a video interview we posted back in December.
Now, we’d like to introduce you to the Jumpstarting Brain Tumor Drug Development Coalition, which is a united community effort to advance brain tumor clinical trial endpoints – a term meaning the “benefits” of a drug to a patient. The Coalition will be sponsoring the two upcoming workshops that are the cornerstone of the Clinical Trial Endpoints Initiative. In addition to the National Brain Tumor Society, the Coalition includes:
To refresh, by bringing together all of the parties (clinicians, researchers, biopharma, patient advocates, philanthropic organizations and the FDA) that are critical to brain tumor drug development, the Coalition aims to achieve the most favorable clinical trials process possible for determining if new treatments are both safe and effective for brain tumor patients.
With a more clear-cut pathway through the regulatory approvals process, further biotech and pharmaceutical investment into brain tumor drug development will be incentivized and early stage treatments showing promise will stand a greater chance of accelerated approval thereby opening a new pipeline for treatments that can help patients.
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On the humanists' side of the Alp, one powerful idea has been the development of X-Bar theory, with its suggestion of a universal grammar at least for phrase structures. Steven Pinker has a superb exposition of the theory in The Language Instinct, and that is what I am adapting here (Pinker, S., The language instinct, 1994, pp. 74-152).
Consider a noun phrase about Hillary Rodham Clinton, the senator from New York from Arkansas The grammatical structure of the phrase consists of a header, "senator," which provides the organization for the rest of the phrase. The header "senator" takes an argument, a property that goes with it: being a senator includes being a senator representing some particular state, hence the senator from New York, header plus argument
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