Clinical Pharmacology Dealing with science // Drug Repurposing

Clinical Pharmacology Dealing with science

And clinical pharmacology

7-1-2011

Abstract

The evolution of enabling technologies and their associated perspectives into molecular mechanisms underlying disease has extended beyond the abilities of scientific and clinical structures to advance their translation into new algorithms that improve the health of patients and populations.1 Research programs have yielded a vast array of novel molecules related to pathophysiological mechanisms that represent diagnostic and therapeutic targets which have the potential for personalized healthcare management. Yet, despite extraordinary scientific advances, routine successful translation of discovery into new therapeutic tools remains a distant vision. Beyond constraints in bridging discovery science with clinical translation due to obstacles in facilities, resources and in skilled specialized investigators, 95% of therapies brought into product development by the pharmaceutical and biotechnology sector eventually fail, reflecting negative balance between efficacy and adverse effects.

Recommended Citation

Waldman, Scott A.; Hohl, R J.; Kearns, G L.; Swan, S J.; and Terzic, A, "Clinical pharmacology as a foundation for translational science." (2011). Department of Pharmacology and Experimental Therapeutics Faculty Papers. Paper 11.

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by Leprechaun58

I find myself in a highly confusing state of affairs at present. Anyone with any college experience ought to be able to sympathize with what I'm going through... any advise would be most helpful.
I spent seven quarters in a BS in nursing program, going through the various rotations... during my second to last quarter, a stupid oversight on a patient case study (failure to cite a source) resulted in my having to withdraw from the clinical course and wait until the present quarter (winter) to re-do the rotation @ Swedish hospital. Up until that point, my GPA was 3.5... worked hard enough and did well enough to get into an exclusive internship and signed a contract to work at a Seattle Hospital come licensure

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