Autoimmune disease in dogs life expectancy // Drug Repurposing

Autoimmune disease in dogs life expectancy

We love to spoil our pets!

Treating canine lupus early will help keep it from affecting Lucy's life span.

Dana Neely/Photodisc/Getty Images

If Lucy is limping around and having difficulty getting up in the morning, you might suspect arthritis. But with your dog's lameness switching from one leg to another, and the presence of scaly, red sores, it's likely something else is wrong. These symptoms, along with testing, may lead your vet to diagnose canine systemic lupus. It's an autoimmune disease that's as serious as it sounds, and it could possibly shorten Lucy's life.

Potentially Fatal

Lupus is a chronic disease meaning once Lucy has it, lifelong treatment will be necessary. She'll have her good days and bad days as the disease goes into and comes out of remission. Becky Lundgren, D.V.M. wrote in her article "Systemic Lupus Erythematosus" for VeterinaryPartner.com that the disease is potentially fatal. Canine lupus is capable of shortening a dog's life because it causes her immune system to attack her own tissues and cells. Occasionally the resulting cell damage can lead to death.

Difficult Diagnosis

Early diagnosis and treatment is the key to keeping lupus from affecting Lucy's life span, but diagnosing it can be difficult. The symptoms are difficult to pin down because not all dogs show the same signs. Additionally, the ones you'll notice, such as fever, lameness and skin and mouth sores will come and go. This can keep you from recognizing the condition as serious. Blood tests have to be done to confirm other symptoms such as anaemia, thyroiditis and antinuclear antibodies.

Prevention is Problematic

The cause of canine lupus isn't known, although some factors have been suspected as having an effect on which dogs develop the disease. Lucy could be genetically predisposed to having canine lupus, or a viral infection or a drug reaction could bring it on. Because of the uncertainty surrounding the cause of lupus in dogs, there's no sure-fire way to prevent any dog from getting it, other than keeping a dog who has it from breeding to avoid perpetuating the disease.

Caring for a Dog With Lupus

Treating Lucy's lupus with immunosuppressive drugs and corticosteroids can reduce the chances of the disease damaging her tissues and cells. That can go a long way toward ensuring the illness won't cut her life short. At home, you can do your part by encouraging rest during her flare-ups, even crating her if necessary to keep her from overexerting. Bright sunlight can increase the frequency of those flare-ups, so helping her to avoid intense sunlight is beneficial. Pet MD notes that if Lucy's kidneys have been affected by the disease your vet likely will put her on a low protein diet, too.

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Sory A-G, but that is incorrect

by chockalot

Excess iodine does NOT cause Hashimoto's. It can complicate Hashimoto's or other thyroid disorder, because iodine affects the way the thyroid functions. But it does not CAUSE Hashimoto's Disease.
Hashimoto's Disease is an autoimmune disorder that has complex causes - maybe genetic, maybe viral, maybe related to childbearing. But diet is not considered one of them.
This is what it says at your link:
"People with Hashimoto's thyroiditis should avoid excess iodine (which can cause hypothyroidism) from natural sources, such as kelp tablets and seaweed

Eh, I'm mad

by Fiona1

So yesterday out of the blue he asks "So when are you going to go to the doctor to control your laziness?"
He was referring to the rheumatologist who will help determine why I had a positive ANA test (likely an autoimmune disease which causes extreme fatigue).
And for the record, despite being very tired 24/7, I am NOT lazy. I work fulltime, don't call out because I'm tired, and do the majority of household chores. Really, the only thing that really suffers because of the fatigue is recrational activities, I'm much less likely to want to go out and have fun or play on the lake or whatever

They think I have

by Dingey_48

Paraneoplastic pemphigus
Though there are many forms of pemphigus, paraneoplastic pemphigus is the least common and most serious. PNP is a rare autoimmune bullous disease that causes blistering. Keratinocytes, which are what make up the epidemus, separate from each other, leaving gaps. Many times the gaps become filled with fluid peel off, leaving the skin raw and open to infection. These blisters usually appear in the mouth, throat, lips, and random places on the skin. The disease is also extremely fatal, as 90% of those diagnosed with the disease die due to sepsis, multi-organ failure, or cancer that caused the disease

Oh, and a defintion: we are dying!

by geekles

Lupus is a chronic, autoimmune disease which causes inflammation of various parts of the body, especially the skin, joints, blood and kidneys. The body's immune system normally makes proteins called antibodies to protect the body against viruses, bacteria and other foreign materials. These foreign materials are called antigens. In an autoimmune disorder such as lupus, the immune system loses its ability to tell the difference between foreign substances (antigens) and its own cells and tissues. The immune system then makes antibodies directed against "self." These antibodies, called "auto-antibodies," react with the "self" antigens to form immune complexes

Saunders Textbook of Pediatric Rheumatology: Expert Consult (Cassidy, Textbook of Pediatric)
eBooks (Saunders)

Erie race will benefit 2 with health issues  — Toledo Blade
Zoie has an autoimmune deficiency and receives monthly life-saving treatment at Mercy St. Vincent Medical Center.

Mosby Rheumatology
eBooks (Mosby)